Trileptal

Reggie has been on Trileptal for 4 weeks, and seizures have improved from baseline. The patterns seems to be 2-3 Grandmal seizures in a 2 day cluster with generalized seizures, every 7 days.

Depakote toxicity

Reggie came to MCH ER Thursday for progressive lethargy, and diarrhea. Diagnosis depakote toxicity and depakote induced thrombocytopenia. His ammonia level was 65, elevated liver enzymes, platelets 103 (383 before depakote).
Unfortunately depakote is the only thing that has ever stopped his seizures, and now we have to come off. Thrombocytopenia is not dose dependent

Naratriptan seizures

Unfortunately, it appears that the naratriptan that is helping Bundy's ataxia so much increases Reggie's seizure activity. We stopped giving it to see if he improves.

Pseudomonas

After 2 1/2 months of this horrible cough with white sputum, I asked for a culture. Since reggie had been treated with IV antibiotics during his december hospitalization, i had a hard time convincing the doctors that this was bacterial. The culture came back positive for pseudomonas and enterococcus. Which is usually a nosocomial infection, so he acquired the pseudomonas during is last hospitalization. I am happy we have a treatable diagnosis. Reggie is in the hospital on IV Zosyn

Ayurveda

Trying a new approach to stabilize Reggie. My main goal right now is to stop his upper resp. Symptoms. Dr. Mooni used a combination of diet (liver, no diary, ginger, turmeric), herbs, massage, and homeopathy. Reggie has been on the regime for 1 week and has about a 50% reduction in symptoms. We have been able to decrease robinol to 1mg once a day.

Botox

Reggie got botox injections. 30cc in bilateral submandibular glands. In 7 days we should see a significant decrease in this saliva production.

Cough

I have spent the last couple weeks trying everything for Reggie cough. We have seen the acupuncturist, chiropractor and homeopath. All remedies didn't improve the cough. Reggie actually began having milk white nasal discharge. After trying everything we started minocycline yesterday. White Sputum is gone, thr cough remains, but not nearly as bad. Reggie is scheduled for Botox injection into the salivary glands Wednesday.